Bioactivity | [Gln144]-PLP (139-151) is an experimental antigen used to study T cells respond to both autoantigens and cross-reactive non-autoantigens. [Gln144]-PLP (139-151) activates T cells by binding to T-cell Receptor (TCR), which triggers an immune response. [Gln144]-PLP (139-151) can be used to study the regulation of autoimmune diseases[1]. |
CAS | 170033-42-8 |
Sequence | His-Ser-Leu-Gly-Lys-Gln-Leu-Gly-His-Pro-Asp-Lys-Phe |
Shortening | HSLGKQLGHPDKF |
Formula | C66H102N20O18 |
Molar Mass | 1463.64 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Munder M, et al. Reduced self-reactivity of an autoreactive T cell after activation with cross-reactive non–self-ligand[J]. The Journal of experimental medicine, 2002, 196(9): 1151-1162. |